【摘要】 将光镜下观察过的人肝癌Hep 3 B细胞G显带染色体标本在扫描电镜下进行观察。在形态学上发现,光镜下染色体G带带纹与扫描电镜下染色体表面形态结构之间有着对应关系。结构畸变染色体,如断裂、易位、双着丝粒染色体、内复制染色体等这些肿瘤细胞染色体的典型改变,都可清楚观察到。应用扫描电镜观察染色体是一项很有实用价值的研究手段。更多还原

【Abstract】 The chromosme structures of the human hepatoma cells in metaphase were examined byScanning Electron Microscopy (SEM) after the observation of G-banding techniques by lightmicroscopy. The circumferential groove subdivides the short and long arms of the chromatidintomany segments. It has shown that the SEM chromosome pattern is similar to the light micros-copic chromosome pattern. The structure of aberrant chromosome also can be detected by SEMTherefore SEM will be an a practical and useful method in the studies of chromosomes.更多还原