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无环鸟苷等与人白细胞干扰素合用治疗单疱角膜炎的临床观察

Combination therapy for herpes simplex keratitis with acyclovir etc and human leukocyte interferon

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【作者】 温任杰; 张美玉; 董世范;

【Author】 Wen Renjie, Zhang Meiyu and Dong Shifan (Department of Opthalmology, Second Teaching Hospital)

【机构】 白求恩医科大学第二临床学院眼科; 白求恩医科大学第二临床学院眼科;

【摘要】 本文报道应用抗病毒药无环鸟苷、病毒唑分别同干扰素(IFN)联合治疗111例单疱病毒性角膜炎病人。结果表明无环鸟苷是强有力的抗病毒新药,值得临床推广使用。

【Abstract】 Herpes simplex keratitis (HSK) patients were treated with acyclovir(ACV) or virazole (VIZ) and human leukocyte interferon (IFN) .ACV and IFN were used in Group A; VIZ and IFN were used in Group B。 The mean healing time for the superficial type of the disease were 6.7 and 10.8 days respectively for these 2 groups> and that for the stromal type of the disease were 10.4 and 15.7 days respectively, Our results indicate that combination therapy with ACV and IFN is more effective than that with VIZ and IFN (P<0.01) .The results also suggest that ACV is a strong antiviral agent and is worthy for being widely used in treatment of HSK.

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