【摘要】 将15只雄性家兔的两侧睾丸摘除,去势后一个月给动物静脉注射内毒素,复制发热模型,实验组动物施以电针,比较实验组及对照组动物的发热高峰(△T)和体温反应指数(TRI),前者差异性显著,后者差异性不显著。血浆睾酮水平与去势前比较,虽有降低但无统计学意义,而血浆雌二醇水平较去势前有明显增加,两者比较其差异性显著。去势后三个月,血浆睾酮水平较去势前有明显减少,去势前和去势后两者相比较其差异性显著。血浆雌二醇水平进一步增加,与去势前比较其差异性非常显著。去势后三个月开始给动物肌肉注射戊酸雌二醇,每天一次连续11天。然后再用内毒素复制发热模型,实验组施以电针,比较两组动物的△T和TRI,其差异性均显著,结果表明针刺抑制动物体温上升和血浆性激素水平有关。更多还原

【Abstract】 Fifteen male white big ear rabbits were orchidectomized on both sides. One month later,B.coli endotoxin was injected intravenously into these rabbits and fever ensued. Electric acupuncture was applied to the experimental animals.There was no significant statistical difference in the temperature response index (TRI) as compared with the control animals. However, the difference in fever peak (ΔT) showed statistical significance, A decrease in testosterone in blood plasma after orchidectomy was observed, without statistical significance at first, whereas levels of estradiol in blood plasma after the operation was increased with statistical significance. Nevertheless, 3 months after operation, the decrease in testosterone levels became much more obvious with marked statistical significance as compared with those before operation .Levels of estradiol showed further increase. Estradiol valerate was then injected into each animal for 11 days and endotoxin was then injected to each of them to develop a fever. Electric acupuncture was applied to the experimental animals, and the difference in fever peak and TRI were of statistical significance as compared with the control group. It is suggested that the effect of electric acupuncture in inhibiting the temperature increase is related to sex hormone levels in blood plasma.更多还原