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中西医结合治疗复发性口疮及尿17-酮类固醇和血清胆碱酯酶观察

Relapsing Aphthous Ulcer Treated with TCM-WM Therapy and Observation on Urinary 17-Ketosteroid and Serum Cholinesterase

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【作者】 华季良; 华挹; 樊英芳; 景寿年;

【Author】 Hun Jiliang Hua Yi Fan Yufang Tianjin First Central Hospital,Tianjin

【机构】 天津第一中心医院; 天津第一中心医院;

【摘要】 本文介绍用中西医结合方法治疗复发性口疮383例,并在治疗前后测定唾液量、尿17-酮类固醇及血清胆碱酯酶。结果发现肾阴虚型患者尿17-酮类固醇值低下(男8.92±2.81,女6.43±1.31),治疗后有所回升(男16.02±2.56,女10.82±0.18);脾虚湿热型患者唾液量较健康人高(4.48±0.90),血清胆碱酯酶值升高(9.27±4.76),治疗后均显著下降(分别为2.76±0.35,1.41±1.03)。治疗前后经统计学处理差异有显著性意义(P 均<0.01),在临床上有一定意义。

【Abstract】 383 mild relapsing aphthous ulcer patients,aged 18~68,over 3 years of history and 2~4 weeks course of disease,were treated with TCM-WM therapy and reported in this article.The amount of saliva,urinary 17-ketosteroid and serum cholinesterase before and after treatment were determined.Results showed that in kidney Yin deficiency patient,the value of urinary 17-ketosteroid output was lowered(mate 8.92±2.81, female 6.43±1.31),and was elevated after treatment(male 16.02±2.56,female 10.82±0.18);while in spleen deficiency patient,the amount of saliva secretion(4.48±0.90)was greater than that of the healthy subjects,their serum cholinesterase increased(9.27±4.76),and was markedly reduced,2.76±0.35 and 1.41±1.03 respectively after treatment.The difference between pre-and post-treatment was significant statistically(P<0.01).This contributed to the clinical practice. Clinical observation on symptoms showed that during the hyperfunction of sympathetic nerve,the basic body temperature tended to elevate,four limbs were wet and hot,heat sensation felt in the chest,palms and soles,thirsty with dry throat,little amount of condensed saliva,urinary 17-ketosteroid tended to lower,these were all conformed to the kidney Yin deficiency;but during the hyperfunction of parasympathetic nerve,the clinical manifestation was just in opposite,especially the patients displayed large amount of diluted saliva, pale and swollen tongue,with teeth marks and white or greasy fur,the serum cholinesterase was tended to increase,these were all conformed to the spleen deficiency as mentioned in this article.

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