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缺血性脑血管病的中医辨证、心功能和血液流变学三者的关系

Relationship among Syndrome Differentiation of TCM,Cardiac Function and Hemorheology in Ischemic Cerebral Vascular Diseases

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【作者】 李其松施永德刘忠英徐伟民吕燕燕秦芝九唐镇生肖保国

【Author】 Li Qisong Shi Yonde Qing Zhijiu Dept.of Neurological Biology,Dept.of Biophysics,Dept.of Neurology,Shanghai Medical University,Shanghai

【机构】 上海医科大学神经生物科学教研室上海医科大学生物物理学教研室上海医科大学神经生物科学教研室上海医科大学神经病学研究所

【摘要】 本文应用心肌收缩力、心室顺应性等血流动力学和全血比粘度、血球压积、血浆比粘度、红细胞电泳和纤维蛋白原等血液流变学指标,对85例缺血性脑血管病进行辨证分型的研究,结果发现:心肌收缩功能减弱者以气阴两虚型最多,为75%;阳虚型45.2%;阴虚型30.7%。血液流变学的五项指标,除反映本病具有不同程度的血瘀的共性外,尚发现不同的中医辨证类型的差异。进一步研究有益于阐明机理和提高疗效。

【Abstract】 Parameters of both hemodynamics such as myocardial contractility and ventricular flexibility,and hemorheology such as whole blood viscosity,hematocrit,plasma viscosity,RBC electrophoretie time and fibrinogen were measured in 85 patients of ischemic cerebral vascular diseases.They were divided into 3 groups,namely,Yang deficiency(阳虚)group,Yin deficiency(阴虚)group and Qi-Yin deficiency(气阴虚) group according to the syndrome differentiation of TCM.The results of hemodynarnics showed that patients with decrease of myocardial contractility belonged chiefly to the Qi-Yin deficiency group(75%),next to it was the Yang deficiency group(45%)and the least was the Yin deficiency group(31%).The results of hemorheology showed that in the above-mentioned three groups there existed the same changes such as the whole blood viscosity and fibrinogen being much higher than that of normal persons,but the Yang deficiency group revealed that it had the highest whole blood viscosity and the slowest RBC electrophoresis,and the Yin deficiency group had the highest plasma viscosity,and the Qi-Yin deficiency group showed that its hemorheological parameter had the intermediate value betwecn the other groups.According to the relationship between hemodynamics and hemorheology,it was concluded that those abnormal in myocardial contractility were even more abnormal in hemorheological tests.

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