【摘要】 作者对109例肺心病瘀证患者和80例对照组九项血液流变学指标测值进行了多因素判别分析。经微机处理,筛选出三个瘀证的判别指标,并建立了在血液流变学意义下瘀证的判别模式。同时对判别模式的正确性进行了临床检验。结果,其诊断效率为83%。瘀证判别函数 f 值随瘀证临床表现减轻而下降的观察,还表明所建立的判别模式对于瘀证微观辨证不仅具有定性意义,而且在一定程度上尚具有定量意义。更多还原

【Abstract】 To differentiate blood stasis syndrome microcosmically in cor pulmonale during acute attack,9 indices in hemorheology were evaluated in 109 patients with stasis and 80 normal adults.Results from the experiment in 65 typical stasis patients and 20 randomly picked normals were fed into a microcomputer for multiple-factor-discrimination analysis.By careful screening,3 of the 9 indices were proved valuable in detection of blood stasis:[they were blood specific viscosity(η_b),concentration of fibrinogen in plasma (Fib)and RBC electrophoretic]mobility(EPM),on the basis of which an discriminative function(f)was found[f=0.00333(η_b-5.173)+0.0000355(Fib-377)-0.0244(0.5 EPM-0.682)].The function,in its turn,enabled the researchers to evaluate the critical value in discriminating blood stasis:a value of(f) superior over or inferior to -0.003335 would suggest presence or absence of stasis respectively.A test to certify the correctness of the function and the critical value in 109 patients with blood stasis and a control group of 20 normal adults revealed that 87 of the 109 patients were confirmed positively,giving a conforming rate 79.8%,whereas not a single case in the control group was erroneously diagnosed as blood stasis syndrome.The effeciency rate m diagnosis was 83%.Observation of the mobile values of(f)prior and posi to a subsequent treatment in 20 randomly selected patients with blood stasis in cor pulmonale showed that the value of(f)descended with improvement of clinical symptoms after a therapy of promoting the blood circulation and relieving the stasis.All these led to a conclusion that the established function(f)and the critical value found in the experiment were of significance in microcosmic syndrome differentiation of blood stasis in cor pulmonale not only qualitatively but,to some extent,quantitatively as well.更多还原