【摘要】 通过对DNP诱发的30例大鼠鼻腔上皮癌变过程的形态学观察,作者认为其癌前病变形式包括上皮异型增生、外突型乳头状瘤、上皮早期浸润、鳞化异型增生和基底细胞异常分化性增生,在组织形态学方面所反映出的共同特点是①增生;②异型性和③异常分化倾向。更多还原

【Abstract】 Precancerous lesions of the nasocavities were induced by a large dose of DNP subcutaneous injection 12-14 times in 45 days in 30 rats. Cancerous lesions developed in all the animals when the observation period prolonged to 160 days. This paper emphasizes on the process of the precanceroms lesiens, which includes dysplasia of columnar epithelium, exophytic papillona, epithelial infiltration, dysplastic metaplasia and abnormally differentiated proliferation of the base cell.There are three mainly common morphological characteristics of the precancerous changes on experimental animals: proliferation, dysplasia and abnormally, differendiated tendency.更多还原