【摘要】 <正> 肾内有丰富的机械感受器和化学感受器。机械感受器分布在肾动脉、肾静脉、肾盂和整个肾皮质,它们对压力的变化敏感。肾内化学感受器分为R₁和R₂化学感受器,R₁化学感受器对肾内缺氧敏感,R₂化学感受器对肾盂内离子成分改变敏感。上述肾内感受器对心血管活动的影响所知不多。在脊髓猫,曾观察到升高输尿管内压引起血压下更多还原

【Abstract】 The effects of renal receptors on blood pressure were observed in anesthestized rabbits with pentobarbital. Both elevation of renal intrapelvic pressure and occlusion of renal vein did not cause significant changes in arterial pressure (AP) in intact rabbits, but elicited significant fall in AP in rabbits with sino-aortic denervation (SAD). Perfusion of renal pelvis with urine and saline and the elevation of intrapelvic pressure also caused significant decrease in AP in rabbits with SAD. After renal denervation, the depressor response was abolished. Perfusion of pelvis with 100 mEq/L of KC1 caused the increase in AP in rabbits with SAD. Occlusion of renal artery did not change AP in rabbits with SAD; but induced the elevation in AP after renal denervation. These data suggest that 1) excitation of renal mechanoreceptors causes reflexly the fall in AP; 2) arterial barore-flex has inhibitory effects on depressor response by excitation of renal receptors.更多还原