【摘要】 本文比较小肠结肠炎耶氏菌毒力质粒阳性株与其阴性变异株在小鼠脾细胞和腹腔巨噬细胞内生长的能力。果表明小肠结肠炎耶氏菌质粒阳性株可在小鼠体内脾细胞中生长,阴性株则否。在腹腔巨噬细胞内,不论体内或体外,两种菌株均不能生长。假结核耶氏菌毒力质粒阳性株与小肠结肠炎耶氏菌相似,但它在脾细胞内的繁殖速度明显高于后者。这些结果提示,小肠结肠炎耶氏菌胞内寄生性与毒力质粒有关,但其胞内生长能力弱于其他种耶氏菌。更多还原

【Abstract】 The growth of Yersiniae in mouse spleen cells and peritoneal macrophage was compared.The results showed that Y.enterocolitica virulent plasmid bearing strain proliferated in vivo in mouse spleen cells,while plasmid cured mutant did not.Both the two strains did not grow in peritoneal macrophages both in vivo and in vitro.Y.pseudo-tuberculosis plasmid bearing strain exhibited similar results as in Y.enterocolitica,but its growth rate in spleen cells was much higher than in the latter.These results suggest that intracellular proliferation of Y.enterocolitica is mediated by the virulent plasmid,but the ability of proliferation is weaker than that of other Yersiniae species.更多还原