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系统性白色念珠菌抗原血症的研究——Ⅰ.从白念菌提取胞壁抗原——甘露聚糖
Investigation on antigenemia of systemic candidiasis Ⅰ.Extrction and purification of surface polysacharide(manna)of Candida albicans.
【摘要】 <正> 白色念珠菌(以下简称白念菌)是一种条件致病菌,在正常情况下不致病或仅引起表浅感染,当机体的抵抗力严重下降时,可能并发条件致病菌感染,引起深部感染,甚至全身播散性感染,其中以白念菌为最多见。此时诊断甚难。为了提高微生物学的诊断效果,近年来,国外有人试从血液中寻找可溶性抗原,以协助确诊。最常被检测
【Abstract】 Specific surface polysaccharide antigen mannan was extracted from a strain ofCandida albicans,isolated from blood of a case of disseminated candidiasis,employingmodified method of Sakaguchi.The final product contained 99% sugar and 0.06% protein.Acid hydrolysis of the sugar revealed it consists of mannose only.In bot himmunodiffusion and immunoelectrophoresis,with anti-Candida albicans serum,it formeda single precipitin band.The above data indicates that surface mannan extracted fromCandida albicans is of high purity.
- 【文献出处】 中国免疫学杂志 ,Chinese Journal of Immunology , 编辑部邮箱 ,1987年03期
- 【被引频次】3
- 【下载频次】90