【摘要】 <正> 黄曲霉素诱发动物肝癌的事实,已被许多实验所证实。严瑞琪等首次报告了BHA对黄曲霉素诱发大鼠肝癌及其他肿瘤有明显的抑制作用。香烟被列为肺癌的致癌物质,已众所周知。Nebert教授提出吸烟会阻止黄曲霉素诱发肝癌的发生,就此,我们作了一批以AFB₁致癌作用体内短期实验模型,探讨香烟对黄曲霉素B₁致肝癌作用的影响。更多还原

【Abstract】 In this study, 15 male ducks in the same crowd were divided into three groups with 5 ducks each:（1） controlled group, （2） AFB₁ group, and （3） AFB₁+cigarette smoke group. The agent of crystalline AFB₁ was dissolved in DMSO and injected intraperitonially. In the AFB₁+cigarette smoke group, the frequency and the size of the precancerous hyperplastic change of hepatocytes were much lower than those in the AFB₁ and controlled groups. It seems that AFB₁+cigarette may help the host against action of aflatoxin in inducing hepatoma.更多还原