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食管癌高发区饮食诱癌实验和致癌物初步检测

An Experimental Induction of Cancer with the Foodstuff and Drinking Water from a High Incidence Area of Esophageal Cancer and Preliminary Detection of Carcinogenic Substances

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【作者】 张振东王凤荣李绍森赵玉环

【Author】 Zhang Zhendong et alHebei Medical College, Shijiazhuang

【机构】 河北医学院河北医学院磁县肿瘤防治所河北省地理研究所

【摘要】 长期用食管癌高发区饮食饲养Wistar大鼠,在23只实验动物中有9例食管前胃发生了癌前病变,2例发生前胃癌瘤。初步检测饮水中有二甲基亚硝胺和其他含氮化合物。饲料中有黄曲霉菌、草酸青霉,交链孢属和镰刀菌等。

【Abstract】 Wistar rats were fed with the foodstuff and drinking water of the high incidence area of esophageal cancer for a prolonged period of time. Among 23 experimental animals, precancerous changes in esophagus or forestomach were found in 9 and cancer of forestomach in 2. Dimethylnitrosamine and other nitrogen compound in the drinking water were found and there were also Aspergillus flavus Link, Penieillium oxalicum, Alternaria Nees and Fusarium moniliforme etc.

  • 【文献出处】 中国肿瘤临床 ,Chinese Journal of Clinical Oncology , 编辑部邮箱 ,1987年01期
  • 【被引频次】2
  • 【下载频次】33
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