【摘要】 本文采用支气管肺泡灌洗、分析灌洗液的方法,对沈阳市两地区飘尘进行毒性比较,看出两地区飘尘均能引起不同程度的大鼠肺急性炎症和肺细胞损伤,同一剂量染毒动物污染区大鼠肺损伤较清洁区为重,并恢复较慢。同时看到飘尘毒性与其理化特性有关。随染毒剂量毒性增强,呈剂量—效应关系。更多还原

【Abstract】 To assess the pulmonary injury of suspended particulates rats were wxpesedby intratracheal instillation of suspended particulate suspension collected fromtwo districs in Shenyang then cellular and biochemical assay of lavage fluidwas conducted to evaluate the pulmonary injury.The results showed that all ch-anges caused by suspended particulates had distinct dose effect relationship.Bothdust samples from industrial and residential district could cause pulmonaryacute imflammation and lung cell damage in some extent, but dust from indu-strial district at same dose level caused more severe damage and lasted longer.The results indicated that toxicity of suspended particulates was related to thedose and chemical component.更多还原