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女贞子煎剂对小鼠免疫系统的作用

EFFECT OF FRUCTUS LIGUSTRI LUCIDI ON IMMUNE SYSTEM OF MICE

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【作者】 戴岳杭秉茜李佩珍

【Author】 Dai Yue, Hang Bingqing~* and Li Peizheng~* (Postgraduate of 1988, ~*Department of Pharmacology)

【机构】 中国药科大学中药药理教研室中国药科大学中药药理教研室中国药科大学中药药理教研室 本校研究生

【摘要】 <正> 女贞子(Fructus Ligustri Lucidi)为中医常用的扶正药,具有滋阴、补肝肾作用,其水煎剂能增强机体的免疫功能,抑制小鼠子宫颈癌,醇提取物能回升环磷酰胺(Cy)所致小鼠白细胞减少。本文研究女贞子水煎剂对小鼠免疫系统的调节作用。

【Abstract】 Fructus Ligustri Lucidi (FLL) decoction ig 12.5g/kg, 25g/kg×7d caused marked increase of the weights of spleen and thymus of young mice, and FLL ig 25g/kg×7d significantly increased the weights of spleen of adult mice and inhibited the clearance rate of iv charcoal particles in mice. FLL ig 12.5g/kg, 25g/kg×7d significantly promoted the production of serum spec ific antibody hemolysins and the level of immunoglobulin G, and FLL ig at the above doses for 5 days significantly enhanced the delayed hypersensitivity reaction of footpad induced by SRBC in mice. These results suggested that FLL is capable of increasing humoral and cellular immune functions and suppressing the phagocytosis of reticuloendothelial system.

  • 【文献出处】 中国药科大学学报 ,Journal of China Pharmaceutical University , 编辑部邮箱 ,1987年04期
  • 【被引频次】83
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