【摘要】 <正> 大蒜素是大蒜挥发油中的一个主要活性成分,其结构为CH₂=CH-CH₂-S-S-CH₂-CH=CH₂,1975年已人工合成。该成分具有较强的抗菌作用,是一种较好的广谱抗菌药。该品为油状液体,具挥发性,有特异蒜臭,不稳定,受空气、光线、温度的影响易氧化变质、聚合沉淀,对人体粘膜有刺激性,故给制剂生产和应用带来不利因素。更多还原

【Abstract】 The solid inclusion complex of liquid garlicin with β-cyclodextrin was studied. The formation of the complex was confirmed by thermogravimetry. Desirable conditions of the preparation of the complex were obtained by orthogonal test with a yield of 93.7%. The content of garlicin in the complex was found to be 11.4±0.39% by UV spectrophotometry. The stability of the complex was also observed. The inclusive garlicin was found to have better stabilities to both light and heat, and much lower in volatility than those of the control. The irritation of the inclusive garlicin to rates’ stomach was found to be lowered.更多还原