【摘要】 对1983—1984年流传于北京、天津、吉林、厦门等地手足口病病人中的36株Cox A₁₆野毒株作了某些生物学性状观察。结果用乳鼠作病毒分离优于用细胞培养分离。然而,所分离到的Cox A₁₆病毒却能适应于MEK、FL一类细胞培养,并使这些细胞产生典型的CPE。从交叉中和试验结果可以看出这些野毒株可能出现抗原性的变异,值得进一步研究和证实。更多还原

【Abstract】 During several epidemics of band-foot-mouth di-sease(HFMD)in Beijing,Tianjin Jilin and Xiamen in1983～1984, 36 wild strains of Coxsackie virus A16were isolated and their biological characteristics werestudied. Coxsackie virus A16 strains obviously showedbetter growth in newborn mice than in cell cultures.However, they could grow and induce typical CPEin some types of cells such as MEK,FL,etc.Resultsfrom cross neutralization tests suggested that anti-genic variations might be present among these strains.This is an interesting subject and further study andconfirmation are necessary.更多还原