【摘要】 本文介绍武汉地区小儿病毒性心肌炎病原调查结果。33例小儿急性心肌炎患者,取其粪便、咽拭子或心肌组织进行病毒分离,并采集患者急性与恢复期血清,用微量中和试验检测对Coxsackie B组6个型病毒的抗体增长情况。结果从26例分离出7株病毒,同时伴有对同型毒株双份抗体四倍或四倍以上增长者4例。1例为CoxsackieB₃,3例为腺病毒。对22例双份血清抗体检测结果:有13例分别对Coxsackie B组2、4、3型抗体有4倍以上增长,阳性率为59％。表明CoxsackieB组病毒为武汉地区小儿病毒性心肌炎重要病因。但腺病毒在病毒性心肌炎中的病原作用亦不容忽视。更多还原

【Abstract】 This study was carried out from 1970-1980. Throat and feces samples for viral isolation were taken from acute children’s myocarditis patients and antibodies to Coxsackie B_1-6viruses were mesured by a microneuralization test.Seven strains were isolated.They were 3 Adenoviruses,1. Coxsackie B₃ virus,1 Echo virus and 2 cnteroviruses.Moderate order associations were present for four patients because 3 Adonoviruses and Coxsackic B₃ virus were isolated from the feces and four fold increase in type specific neutralizing antihodies were demonstrated.Thirteen 59％ of 22 patients ahowed a four fold, or higher antibody increase in paired serum samples against Coxsackie B_2-4 viruses.These findings agree with some previous studies suggesting that the Coxsackie B gronp and Adenovirus amy in some cases play the causal tole in myocarditis.更多还原