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油菜蜂花粉及其丙酮提取物对免疫增强作用的研究

IMMUNOENHANCEMENT ACTIVITY OF BEE POLLEN AND ITS ACETONE EXTRACT IN MICE

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【作者】 钱伯初臧星星戚宝凤毛丽珍席玉莲

【Author】 Qian Bochu, Zang Xingxing, Qi Baofeng, Mao Lizhen, Xi Yulian(Zhejiang Academy of Medicine, Hangzhou)

【机构】 浙江医学研究院浙江医学研究院 杭州杭州杭州

【摘要】 本文观察了油菜蜂花粉及其丙酮提取物对正常和由于免疫抑制剂环磷酰胺、荷瘤及抗淋巴细胞血清所致免疫低下小鼠的免疫增强作用。结果表明,蜂花粉及其丙酮提取物对正常幼年和成年小鼠能提高血清抗SRBC抗体的含量(HC50)和增加脾脏空斑形成细胞(PFC)。蜂花粉丙酮提取物对环磷酰胺、荷瘤及抗淋巴细胞血清等所致免疫低下小鼠的血清抗SRBC抗体、定量脾细胞体外分泌抗SRBC抗体(QHS)、脾脏空斑形成细胞(PFC)和特异玫瑰花形成细胞(SRFC)减少均有明显对抗作用。上述结果提示,油菜蜂花粉及其丙酮提取物有免疫增强作用,丙酮提取物可能是该花粉所含一种增强兔疫作用的活性物质。

【Abstract】 Immunoenhancement activity of bee pollen and its acetone extract was studied in normal, sarcoma-180 bearing, cyclophosphamide- and antilymphocyte serum-treated mice.Bee pollen and its acetone extract given orally for 30 days could significantly increase the production of serum anti-SRBC hemolysin (HC50) and the number of spleen plaque forming cells (PFC) in primary response to sheep red blood cell (SRBC) in young and adult mice. The acetone extract of bee pollen could significantly prevent the decrease of HC50) the number of PFC and specific rosette forming cells (SRFC), and the quantitative hemolysin of spleen cells (QHS) against SRBC in S-180 bearing, cyclophosphamide- and antilymphocyte serum-treated mice respectively.These results suggested that bee pollen of Brassica campestris L. and its acetone extract have immune-enhancement activity.

  • 【文献出处】 营养学报 ,Acta Nutrimenta Sinica , 编辑部邮箱 ,1987年03期
  • 【被引频次】16
  • 【下载频次】128
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