【摘要】 自五灵脂中分离得到13种化合物。根据化学方法及光谱(UV,IR,MS,¹H-NMR,¹³C-NMR)分析,其中晶V为一新的异海松酸的衍生物,命名为五灵脂酸。并鉴定其它9种化合物为邻苯二酚（Ⅰ）、苯甲酸（Ⅱ）,3-蒈烯-9,10-二羧酸（Ⅲ）尿嘧啶（Ⅳ）,间羟基苯甲酸（Ⅵ）,原儿茶酸（Ⅶ）,次黄嘌呤（Ⅺ）,尿囊素（Ⅻ）,L-酪氨酸（ⅩⅢ）。化合物Ⅰ～Ⅶ在体外有明显的抑制血小板聚集活性;Ⅰ,Ⅲ,Ⅴ,Ⅶ显示了不同程度的抗菌活性。更多还原

【Abstract】 Thirteen constituents were isolated from the excreta of Trogopterus xanthipes Milne-Edwards, and nine of them were identified as pyrocatechol（Ⅰ）, benzoic acid（Ⅱ）, 3-caren-9,10-dicarboxylic acid（Ⅲ）, uracil（Ⅳ）, m-hydroxy benzoic acid（Ⅵ）, protocatechuic acid（Ⅶ）, hypoxanthine（Ⅺ）, allantion（Ⅻ）, L-tyrosine（ⅩⅢ）. All of them were first reported to occur in the excreta of Trogopterus xanthipes Milne-Edwards. A new compound, wulingzhic acid（Ⅴ） was elucidated on the basis of spectral data (IR, MS, ¹H-NMR, ¹³C-NMR). Pharmacological experiments showed that compounds（Ⅰ）～（Ⅶ） inhibited markedly the aggregation of platelet in vitro, and （Ⅰ）, （Ⅲ）, （Ⅴ）, （Ⅶ） have antibacterial activities to different dgerees. Structure determination of the other compounds is still underway.更多还原