【摘要】 <正> 益肤酰胺是近来由沈阳药学院与大庆市第一医院发现的一种治疗痤疮新药,疗效确切。它是复方乙酰水杨酸片灼烧后的产物,经分离和光谱鉴定证明为N-(4-乙氧苯基)-2-羟基苯酰胺,结构如(Ⅰ),合成方法已有报道。为了验证其化学结构和探讨合成方法,我们进行了化学合成。更多还原

【Abstract】 On the basis of spectroscopic analysis, Efuamide has been confirmed to be indentical with the compound obtained from the residue of ignited APC tablets.In pharmacological experiments, Efuamide was found to have immunosuppressive, antihistaminic and antiinflammatory actions.It showed desirable effect in clinical trial on acne.更多还原