【摘要】 <正> 野菊花（Chrysaenthemum indicum L.）为我国常用中药。1962年陈政雄等从中提得一内酯化合物,熔点213℃,分子式C₁₅H₁₈O₄。1963年钱名堃等进一步作结构研究,认为是一新的洋甘菊薁烃（chamazulene）型的倍半萜内酯,定名为野菊花内酯（yejuhua lactone）,并更多还原

【Abstract】 Yejuhua lactone (C₁₅H₁₈O₄)was isolated in 1962 from yejuhua （the flowers of Chrysanthemum indicum L.）, a commonly known Chinese medicinal herb. It was considered as a new sesquiterpene lactone with guainolide type whose partial structure was postulated in the following year, but the full structure remains unsolved.In this paper, the early empirical formula and some experimental results have been revised. On the basis of our studies, it is shown that the compound is a diguainolide with the formula of C₃₂H₄₀O₈·By comparison of spectral data (IR, ¹H NMR and ¹³C NMR), yejuhua lactone is proved to be the same compound as handelin the structure of which was elucidated by V. A. Tarasov et al in 1976.更多还原