【摘要】 我们在对十多个A、B环上有羟基取代的甾体皂甙元~1H NMR谱研究时发现,△~5-系列的甾体皂甙元1β-OH对19-Me的吡啶溶剂位移为0.30ppm,5β-系列的甾体皂甙元其1β、5β、6β-OH对19-Me的吡啶溶剂位移大约各自为0.15ppm,与不具有1β、5β或6β-OH的甙元相比较,其19-Me的化学位移(吡啶为溶剂)随1β、5β和6β-OH取代数目的增加而向低场位移约0.3、0.6和0.9ppm,并具有可加和性。更多还原

【Abstract】 On the studies of the 1H NMR spectra of steroidal sapogenins which have some hydroxy groups in ring A and B, we found that 1β-OH solvent shift of d5-pyridine on 19-Me are about 0.30 ppm, in △5-series; 1β-, 5β-, and 6β-OH solvent shifts of d5-pyridine on 19-Me are about 0.15 ppm, respectively, in 5β-series. Comparing with the sapogenins which have no OH of 1β-, 5β-, and 6β-positions, we found that the 19-Me chemical shifts (in C5D5N) of sapogenin-shaving 1β-OH, 1β-, 5β-OH, and 1β-, 5β-, 6β-OH shift to lower field about 0.3, 0.6 and 0.9 ppm, respectively.更多还原