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测定血清甲状腺球蛋白在诊断甲状腺癌术后复发与转移中的价值

An Evaluation of Serum Thyroglobulin for the Diagnosis of Local Reccurrence and Metastasis in Patients with Thyroid Cancer after Operation

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【作者】 沈江帆洪爱英崔振兴张光正

【Author】 Shen Jiangfa et al The Central Hospital of Puto District,Shanghai

【机构】 上海市普陀区中心医院西宁钢厂医院上海市普陀区中心医院 进修医师

【摘要】 本文应用HTg RIA法测定了50例甲状腺癌(简称甲癌)术后病人。其中23例经X线摄片或131I全身显像证实转移的分化型甲癌者,其Tg值为6.0~1000ng/ml,平均226ng/ml。(我院正常值<15ng/ml)6例髓样癌及11例分化型未转移甲癌病人,其Tg平均值分别为2.5ng/ml及5.2ng/ml。同时测定了5例分化型甲癌病人,其131I治疗后的Tg值变化情况。我们认为,血清Tg值对检测甲癌术后病人有否复发及转移,是一种简便、有效的方法。

【Abstract】 Serum thyroglobulin measured by RIA method was carried out in 45 thyroid cancerpatients postoperatively.23 nonmetastatic cases of differentiated carcinoma showedtheir range of thyroglobulin 6.0-1000 ng/ml,with average of 226ng/ml (normal 15 ng/mlin this hospital).For the metastatic patients,6 with medullary cancer,11 withdifferentiated thyroid cancer,their respective range of thyroglobulin was 2.5 ng/ml and5.2 ng/mg.Serum thyroglobulin of 5 patients suffering from diffe-entiated carcinomaof the thyroid treated by (131)~Ⅰ for 2-9 months had also been determined.All the findingsshowed that measurement of serum thyroglobulin by RIA method was sensitive andvaluable in assessment of local recurrence or distant metastasis.

  • 【文献出处】 江苏医药 ,Jiangsu Medical Journal , 编辑部邮箱 ,1987年08期
  • 【被引频次】2
  • 【下载频次】81
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