【摘要】 本文对尿δ-ALA 在筛检铅中毒和铅吸收中的实用意义进行分析。晨尿δ-ALA≥6mg/l 同尿 Cp(阳性)或晨尿 Pb(≥0.08mg/l)作为联合指标,其敏感度分别为60.0%和88.0%,高于任一单项指标,而特异度分别为93.3%和84.9%,很适用于初筛。以全日尿δ-A LA≥6 mg/l 为诊断值,其特异度高达100%,然敏感度仅12.0%,故不宜单项用于诊断。如其诊断值改为≥5mg/l 或≥4 mg/l,虽其敏感度有所增高,但特异度却明显减低。更多还原

【Abstract】 Practical value on δ-amino levulinic acid(δ-ALA)in urine for screening of lead poisoning cases were analysed.The combined sensi- tivity of δ-ALA≥6mg/l & coproporphyrinuria of the first morning urine specimen was 60.0% while that of(Cp)or δ-ALA≥6mg/l & lead(Pb)≥0.08mg/l was 88.0%,which was higher than any single index,& the specificity was 93.3% & 84.9% respectively.The specificity of δ-ALA≥6mg/l in 24 h urine specimens was highest (100%)but the sensitivity only 12.0%.Therefore this single index was not useful for diagnosis.If the above diagnostic level changes for ≥5mg/l or ≥4mg/l,the specificity lowers although the sen- sivity rises.更多还原