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瑞香素对心血管影响的药理研究
EFFECTS OF DEPHENETIN ON PERIPHERAL RESISTANCE AND CARDIOTONIC ACTION
【摘要】 瑞香素能降低麻醉狗的后肢血管、椎动脉和冠脉左旋支阻力,增加狗的心输出量(阻抗法),并能增加豚鼠心房肌的收缩幅度。证明瑞香素具有舒张外周血管和一定的正性肌力作用。
【Abstract】 A study was made on the effects of Dephenetin on vascular resistance and cardiotonic action in anesthetized dogs. The results showed that Dephenetin reduced left coronary cifcumflexus, vertebral and femoral ateries resistance, it increased cardiac out put without significant heart rate changes.The results also showed that Dephenetin dilates peripheral vessels and produced positive inotropic action.
【关键词】 瑞香素;
外周血管阻力;
心脏指数;
左心房;
收缩力;
【Key words】 Dephenetin; periperal rascular resistance- cardiac output, positive inotropic action;
【Key words】 Dephenetin; periperal rascular resistance- cardiac output, positive inotropic action;
- 【文献出处】 中国药理学通报 ,Chinese Pharmacological Bulletin , 编辑部邮箱 ,1987年05期
- 【被引频次】16
- 【下载频次】78