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紫海胆提取物SNC的药理研究——Ⅰ.雄激素样活性和免疫增强作用探讨

PHARMACOLOGICAL STUDY OF STRONGYLOCENTROTUS NUDUS EXTRACTES I. The investigation of androgen-like activity and immunological action

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【作者】 高辉陈淑梅李领华刘镁郭海燕何志坚杜玉欣王大芬

【Author】 Gao Hui, Chen Shumei, Li Linghua et al{ Dept. of Pharmacology, Shandong Institute of Marine Material Medica, Qingdao )Du Yuxin Wang Dafen( Dept. of Microbiology, Shandong Insitute of Marine Material Mediea, Qingdao )

【机构】 山东省海洋药物科学研究所药理研究室山东省海洋药物科学研究所山东省海洋药物科学研究所 青岛青岛青岛

【摘要】 紫海胆长期为沿海渔民所食用,经提取得紫海胆提取物SNC。药理实验证明,SNC有雄激素样活性,能明显增强机体免疫功能,升高血红蛋白,增强小鼠运动耐力等作用。未见毒副反应。

【Abstract】 Strongylocentrotus nudus tastes nice and is a popular food among the fishermen living along the seaside. SNC ( Strongylocentrotus nudus Compound ) has been extracted from Strongylocentrotus nudus. The recent experiments in our laboratory showed that SNC had an andro-gen-like effect in rats and it could strengthen the immune activity in mice, increase the hemoprotein in mice and increase the animal-organism movement resistance.The toxic experiment showed that SNC exhibited no toxicity in mice and dogs. Therefore SNC will be a potential marine drug worthy of further studies.

  • 【文献出处】 中国药理学通报 ,Chinese Pharmacological Bulletin , 编辑部邮箱 ,1987年03期
  • 【被引频次】11
  • 【下载频次】151
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