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艾司唑仑与安定对81例精神病人失眠的双盲对照研究

Eighty-one psychoneuroses with insomnia treated by estazolam and diazepam under double blind study

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【作者】 赵友文许迪

【Author】 ZHAO You-Wen, XU Di (Institute of mental Health, Beijing Medical university, Beijing 100083)

【机构】 北京医科大学精神卫生研究所北京医科大学精神卫生研究所 北京 100083北京 100083

【摘要】 艾司唑仑是苯二氮类的衍生物,具有抗惊厥及镇静等作用。本文用艾司唑仑4mg与安定10mg作双盲对照,研究这2药对精神病人抗焦虑、治疗失眠和抗兴奋的疗效。结果表明,艾司唑仑对精神病人各种睡眠障碍均有疗效。艾司唑仑4mg的安眠作用较安定10mg为佳,未发现它的抗焦虑作用。

【Abstract】 Estazolam, same as diaze-pam, is a derivative of benzodiazepine. Both of them have anticonvulsive, sedative effects. Eighty-one psychoneuro-ses with anxiety, insomnia and excitation were treated by estazolam and diaze-pam under double blind study. Results indicated that estazolam(4mg,im)is more effective than diazepam(10mg,im )for all eases with different kinds of psychic disturbance. They can reduce excitements to certain extent but none has any apparent anxiolytic effect. Side effects were milder and less in cases receiving estazo-lam than those of diazepam.

【关键词】 艾司唑仑安定睡眠障碍双盲法
【Key words】 estazolamdiazepamsleep disordersdouble-blind method
  • 【被引频次】3
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