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缺硒对鸡胰腺影响的病理组织学观察

HISTOPATHOLOGICAL OBSERVATION ON THE PANCREAS OF CHICKS FED ON SELENIUM-DEFICIENT DIETS

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【作者】 黄美玉金月英

【Author】 Huang Meiyu, Jin Yueying ( Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China )

【机构】 中国农科院畜牧研究所中国农科院畜牧研究所

【摘要】 用1日龄来航公雏,进行两次试验。第一次试验,将180只雏鸡按体重平均分为两组,每组90只。试验组喂低硒基础日粮(含硒0.01ppm),对照组在基础日粮中补硒至0.20ppm。试验于6、12、18、24、30日龄时分批进行剖检。每次随机从各组取6只做胰腺的病理组织学观察。 第二次试验,将275只雏鸡按体重平均分成5组,每组55只,日粮含硒水平为0.01ppm、0.025ppm、0.05ppm、0.10ppm、0.20ppm。试验于39日龄时随机从每组取5只进行胰腺的病理组织学观察。 结果,低硒组6日龄时,胰腺腺泡上皮细胞胞浆内出现空泡,12日龄时多数与6日龄的变化几乎相似;18日龄时,腺泡上皮细胞胞浆内出现玻璃小体,并有腺泡轻度萎缩;24日龄时胰腺组织的实质内空泡剧增,呈蜂窝状,部分区域的腺泡萎缩,间质开始纤维化;30日龄时胰腺组织的部分区域出现纤维化;39日龄时日粮硒水平0.01ppm组胰腺组织大部分区域出现纤维化。日粮硒水平0.025及0.05ppm组胰腺组织的部分腺泡严重萎缩或轻度纤维化。日粮硒水平0.10ppm组胰腺组织轻度纤维化或腺泡萎缩。两次试验只有0.20ppm组,除个别胰腺实质中出现少量的空泡外,其余未见异常变化。作者初步认为,鸡日粮中硒的含量以0.15~0.20ppm为适宜。

【Abstract】 Histopathological observation of the pancreas in chicks fed on Se-deficient diets was carried out in 2 trials. In trial 1. 180 1-day-old chicks were randomy divided into treated(90 chicks)and control(90 chicks) groups fed on diets containing 0.01 and 0.20 ppm selenium respectively. Six chicks in each group were slaughtered at 6, 12, 24, 30 days of age, and the pancreas were histologically observed. In trial 2. 275 1-day-old chicks were randomy divided into 5 groups ( 55 chicks in each ) and fed on diets containing 0.01, 0.025, 0.05, 0.1 and 0.20ppm selenium. Five chicks from each group were slaughtered at 39 days of age. The results of observation were as follows:A few cytoplasmic vacuoles were found in the acini of control chicks by 6 days and by 12 days, Hyaline bodies appeared and slight acinar atrophy occurred by 18 days. The vacuoles increased greatly in number, giving a honeycomb appearance, and acinar atrophy occurred in some areas: slight fibrosis of interacinar tissue occurred by 24 days. Fibrosis and acinar atrophy of the pancreas appeared by 30 days. By 39 days severe fibrosis occurred. Various degrees of atrophy/slight fibrosis of some acini were found at 39 days in chicks fed on diets containing 0.25, 0.05 and 0.lppm of selenium. Except a few vacuoles in one or two pancreas, abnormal changes were not found in chicks fed on diets containing 0.20ppm Se in both trials. It is assumed that optimum content of Se in diets for chicks is 0.15-0.20ppm,

  • 【文献出处】 畜牧兽医学报 ,Chinese Journal of Animal and Veterinary Sciences , 编辑部邮箱 ,1987年02期
  • 【被引频次】10
  • 【下载频次】86
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