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7—16岁女生血清E2含量与青春期发育

Serum estrodial level and pubertal ehanges in Chinese girls aged 7—16

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【作者】 邴琛王文英张国栋徐苏恩周扬南

【Author】 Bins Cben, etal., Department of Child and Adolesent Health school of Public Health, Shanghai Medical Uuiversity, Shamghai,

【机构】 上海医科大学儿少卫生学教研室上海医科大学儿少卫生学教研室上海市南市区卫生防疫站

【摘要】 本文报导了170名7—16岁女生血清雌二醇(E2)含量并分析了它与青春期发育的联系。在青春期前E2分泌量很低,从10岁起开始增加,12—14岁E2分泌量出现较大幅度的增加,与女性进入青春期性发育阶段相吻合。在第二性征发育进程中,E2含量逐步升高,并且达成年女子水平的百分率亦呈增高趋势。有、无初潮的同龄女生E2含量比较示,12岁组来潮者E2含量明显高于同龄未潮者。随妇科年龄的增加,E2分泌量达成熟女子水平的百分率上升,妇科年龄≥3岁时,73%的女生E2测量值达到成热女子的水平。

【Abstract】 Serum estrodial(E2) measured by RIA method in 170 healthy girls from 7 to 16 years old was cerreiated with pubertal development. Serum E2 level was very low in girls betwcen the ages of 7—9 and from 10 years old on it hegan to increase E2 seeretien increased drastically. This phcnomena was in agreement with the eutering of pubertal Sex maturation period. E2 level iacreascd Progressively with secondary sex characteristic development and the percentage which reached the adult level inereased also .Comparasion of E2 Ievels between Pre and post menarcheal girls showed that E2 level was significantly higher in postmenarcheal group than premenarcheal group.With the increasing of gynecological age, the Percentane of E2 level attained to the level of adult women increased too. 73% subjects studied reached the Ievel of maturaed females when gynecological age were 3 years.

【关键词】 雌二醇青春期女生生长发育
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