【摘要】 <正> 针刺对痛情绪反应的抑制效应与边缘系统,尤以海马的机能有较密切的关系。形态学以及电生理实验均表明,脑内存在中缝-海马及蓝斑-海马通路。我们也曾看到,电针和刺激背中缝核(NDR)、蓝斑核(LC)皆可明显抑制海马锥体细胞层单位自发放电,损毁 LC 后针刺压抑海马放电更多还原

【Abstract】 Role of n.dorsal raphe（NDR）and the serotoninergic receptor anta- gonist-cyproheptadine on electroacupuncture（EA）regulating the spontan- eous discharges of units in the dorsal hippocampal pyramidal layer at the CA₂ and CA₃ regions was studied in rats anesthetized with urethane.The spontaneous activities were mostly inhibited by EA at aeupoint“Jiaji” or“Zusanli”. After NDR lesion or intravenous injection cyproheptadine the freque- ncy of hippocampal spontaneous activity in some cells was increased and the pattern of firing in some cells was changed.The spontaneous discha- rge of hippocampal cells mainly turned by to be enhanced the EA. This result suggests that the NDR and serotonin may play a role in the pathway mediating the EA effect on hippocampal cell activity.更多还原