【摘要】 本文对109名8～21岁的健康男性儿童青少年进行了急性饮食盐负荷下肾脏排钠功能的研究。结果表明,有原发性高血压家族史的血压正常对象,相对于无家族史的对象负荷后尿排钠量少,负荷排钠反应慢且弱。结果提示:有原发性高血压家族史的儿童,可能在高血压病发病前就已存在遗传性肾脏排钠功能缺陷。更多还原

【Abstract】 Experimental study was done on the kidney function of sodium excretion in 109 healthy male children and youths from 8-21 years old. Urinary Na was measured after acute oral sodium loading. The result showed that the subjects with normal blood pressure and with family history of essential hypertension excreted less Na in their urine than the subjects without family history after loading. The response of sodium excretion to loading was slower and weaker in the subjects with family history. The result suggests that the children with family history of essential hypertension seem to have herecitary functional defect in the excretion of sodium after acute oral sodium loading before developing hypertension.更多还原