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氯醚避孕针对基础体温、阴道细胞、宫颈粘液及子宫内膜的影响

Effects of €hlormadinone-Quingestanol, a Long-acting Injectable Contraceptive, on Basal Body Temperature; Vaginal Cytology, Cervical Mucus and Endometrial Histology

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【作者】 陈文静张龙生沈继云杨宜弟

【Author】 Chen Wenjing, Zhang Longsheng, Shen Jiyun, Yang Yidi Family Planning Research Institute, Tongji Medical University, Wuhan

【机构】 同济医科大学计划生育研究所同济医科大学计划生育研究所

【摘要】 本文报告21例注射氯醚避孕针妇女的子宫内膜活检结果,系统观察14例基础体温及6例宫颈粘液、阴道细胞的变化。在药物的影响下,宫颈粘液的pH值、拉丝度下降(P<0.05,P<0.01),宫颈粘液结晶形成受抑(P<0.01),子宫内膜呈退行性变。提示氯醚避孕针避孕环节是多方面的:改变宫颈粘液理化性质和干扰子宫内膜与孕卵的同步关系。

【Abstract】 Endometrial histology has been studied in 21 healthy women receiving chlormadinone-quingestanol long-acting injectable contraceptive. Changes of BBT in 14 cases and cervical mucus and vaginal cytology in 6 cases have been observed systematically. Under the influence of drug treatment pH value and spinnbarkeit of cervical mucus decreased. Crystalization of cervical mucus was inhibited. En-dometrium showed some regressive changes. The antifertility effect of chlormadi-none-quingestanol long-acting injectable contraceptive may be suggested due to multiple factors: changes of physicochemical properties of cervical mucus and desyn-chronization of endometrium-blastocyte.

  • 【文献出处】 同济医科大学学报 ,Journal of Tongji Medical University , 编辑部邮箱 ,1987年01期
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