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结核性和恶性胸腹水铁蛋白测定的临床意义
Significance of Ferritin Determination in Tuberculous and Malignant Pleural Effusion and Ascitic Fluid
【摘要】 本文报告用放射免疫分析法对45例胸水进行了铁蛋白浓度的测定。9例恶性胸腹水(其中一例是腹水)的铁蛋白浓度为1429±264ng/ml,36例结核性胸水的铁蛋白浓度为515±51ng/ml,两者差异非常显著(P<0.01)。本文研究结果表明;胸腹水铁蛋白浓度>1000ng/ml即可考虑为恶性胸腹水(特异性为91%,敏感性为78%)。因此,胸水铁蛋白的测定可作为鉴别良、恶性胸水的良好指标。
【Abstract】 The concentration of ferritin in 45 cases of pleural effusion and ascitic fluid were determined by radioimmunoassay, in which the mean±standard error of 9 cases with malignant pleural effusion and ascites was 1429±264ng/ml, and that of the other 36 cases with tuberculous pleural effusion 515±51ng/ml. A comparison between both groups showed marked difference(P<0.01). The result indicates that the malignant pleural effusion can be considered when ferritin level is in excess of 1000 ng/ml (specificity 0.91 and sensitivity 0.78). Therefore, the determination of ferritin concentration in pleural effusion and ascites is of great value in the diagnosis and differential diagnosis of the malignant and benign effusion
【Key words】 SUBJECT HEADINGS: tuberculosis neoplasms ferritin radioimmunoassay;
- 【文献出处】 铁道医学 ,Railway Medical Journal , 编辑部邮箱 ,1987年05期
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