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宫内节育器引起月经过多者纤溶酶元,纤溶活性,过氧化氢酶变化及维生素E治疗观察

CHANGES OF PEROXIDASE, PLASMINOGEN AND FIBRINOLYTIC ACTIVITY ON MENORRHAGIA INDUCED BY IUDs AND THE EFFECT OF TREATMENT WITH VITAMIN-E

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【作者】 张鹏程樊瑞琴陈晓梅

【Author】 Zhang Peng-chertg Fan Rui-qin Chen Xiao-mei(Department of Biochemistry, Family Planning Institute of Hebei Province)

【机构】 河北省计划生育研究所生化研究室河北省计划生育研究所生化研究室

【摘要】 本文对31例置器妇女月经血量过多者的月经血和外周血中纤溶酶元、纤溶活性及过氧化氢酶含量进行了测定。同时观察了20例月经过多者维生素E治疗前后月经血量和过氧化氢酶含量的变化。结果表明,月经血中纤溶活性、过氧化氢酶含量显著增高(P<0.01),外周血则无统计学差异(P>0.05).维生素E治疗后月经血量下降率为35.21%,过氧化氢酶有明显降低(P<0.01)。提示IUD_S引起月经血过多与纤溶活性及过氧化氢酶之间有密切关系。但IUD_S对子宫出血的影响仅限于局部。

【Abstract】 The plasminogen, fibrinolytic activity and peroxidase in menstrual and peripheral blood were measured in 31 menorrhagia women with IUD_s. At the same time, the quantity of menstrual blood and the change of peroxidase were also observed in 20 menorrhagia women before and after vitamin E treatment. It were found that the fibrinolytic activity and peroxidase in menstrual blood of those patients were higher than the normal control group (P<0.01) while the changes of the peripheral blood did not differ significantly(P>0.05). After vitamin E treatment, the quantity of menstrual blood decreased 35.21%. The peroxidase activity significantly decreased (P<0.01). The results indicate that the excessive uterine bleeding induced by IUDs is ralated to fibrinolytic activity and peroxidase and their actions are local.

  • 【文献出处】 生殖与避孕 ,Reproduction & Contraception , 编辑部邮箱 ,1987年03期
  • 【被引频次】1
  • 【下载频次】13
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