【摘要】 120例系统性红斑狼疮,贫血占76.7％,白细胞减少33.3％,血小板减少49％。肾炎型和混合型的病例,其贫血的发生率要高于皮肤型者(P<0.001)。10/58例贫血患者(17.2％)Coombs试验阳性,但伴溶血性贫血者仅2例。19/40贫血病例(47.5％)血清铁和总铁结合力均降低,血清铁降低而TIBC增高者仅3例。24/30(80％)贫血患者血清铁蛋白高于25ng/ml,而血液锌原卟啉高于80μg/dl仅4/29例贫血患者。本文还报告2例SLE伴有典型再生障碍性贫血。更多还原

【Abstract】 Among 120 cases of systemic lupus erythematosus (SLE), anemias were found in 76.7％, leukopenia in 33.3％ and thrombocytopenia in 49％. The incidence of anemia was higher in the patients with nephritis type or mixed type of SLE than in patients with skin type of SLE (P<0.001). Positive Coombs test was found in 10 of 58 anemic patients (17.2％), but only 2 of them had hemolytic anemia. Low serum iron with low TIBC was found in 19 of 40 anemic patients(47.5％), and low serum iron with high TIBC only in 3 cases. Serum ferritin more than 25 ng/ml was found in 24 of 30 anemic patients (80％) and zinc protoporphyrin more than 80 μg/dl only in 4 of 29 anemic patients. In addition, 2 cases of SLE with typical aplastic anemia are reported.更多还原