【摘要】 本文报告自1984年5月～1985年10月对40例无精症患者采取外周血淋巴细胞作体外培养,染色体制片,作GTG、CBG显带镜下及照相核型分析,必要时加高分辨G带(HRC)或银染(NOR-AS)分析,并作了C带异态性研究和家系调查,结果如下:(1)数目异常9例(22.5％);(2)结构异常3例(7.5％):(3)异态性19例(47.5％);(4)核型正常无异态性者9例(22.5％)。部分病例测宠血HCG、LH、FSH、T,血、精液锌含量,和睾丸电镜检查及输精管X线造影。更多还原

【Abstract】 In 40 infertile males with azoospermia, chromosomal preparations made from peripheral blood lymphocytes were analyzed by conventional method and additionally by high resolution chromosome G-banding and silver-staining (NOR-Ag) in some cases. The result showed (1) sex-chromosome abnormalities in 9 cases (22.5％),including 45, XY 1 case, 47,XXY 7 cases and 46.XY/47.XXY 1 case; (2) autosomal deletion in 3 (7.5％); (3) variant chromosome in 19 (47.5％); and (4) normal karyotype in 9 (22,5％).The results indicated that cytogenetic screening for male infertility and subfertility may be of value.更多还原