【摘要】 8个医疗单位外环境及医疗器械采集混合样本187份,乙型肝炎表面抗原(HBsAg)阳性率4.48％,且阳性率随着被血液污染程度的增加而上升。“常规消毒”后医疗器械仍有2.78％阳性。1～2％新洁尔灭及1～2％过氧乙酸对高滴度(1:25 600)HBsAg无作用,但对低滴度(1:3200)有一定作用。现场消毒液浓度符合率仅60％。采集消毒液经超离心后9只样品中有8只HBsAg阳性,电镜下见到乙型肝炎病毒(HBV)三种颗粒:球形、管形及Dane颗粒。提示某些医疗单位具有乙肝医源性传播的可能性。更多还原

【Abstract】 Of 187 mixed samples taken at random from surfaces of medical instruments in eight hospitals, 24 (4.48%) were positive for HBsAg. The positive rate rose with increased intensity of blood contamination. There was still a 2.78% positive rate after routine disinfection. Standard disinfectants 1/1000 or 2/1000 Bromo-geremine, and 1/1000 or 2/1000 Peracetio acid could destroy low titre HBsAg, but couldn’t destroy high titre HBsAg. Only 60% disinfective solution obtained commonly used in the field reached the standard titre, but they inactivate HBsAg same as the standard disinfective solution.Nine samples of disinfeotive solution from the field were centrifuged, and eight out of the nine sediments proved to be HBsAg positive. Electron microscopic examination revealed three morphologic forms of HBV: spherical, tubular and Dane particles. These facts suggest that currently, iatrogenio transmission of hepatitis B is possible in some hospitals.更多还原