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青海地方性克汀病垂体——甲状腺轴与生长发育关系的研究

ARESEACH OF THE RELATIONSHIP BETWEEN PITUITARY-THYROID AXIS AND PHYSICAL DEVELOPMENT IN QINGHAI ENDEMIC DISEASE

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【作者】 尤传一; 陈云亭; 韻得中; 李纯杰; 金成恩; 安永清; 刘东风;

【Author】 You Chuanyi,et al Qinghai Province people’s Hospital

【机构】 青海省人民医院; 青海省人民医院; 青海省地方病防治研究所;

【摘要】 本文报告青海省42例地方性克汀病垂体——甲状腺轴与生长发育的关系。CT扫描显示克汀病患者垂体增大。垂体高度与血清TSH正相关(r=0.511,P<0.001),与TT4负相关(r=-0.377,P<0.65)。克汀病惠者血清TSH升高,以粘液水肿型最明显。克汀病患者生长发育延迟,CT扫描显示头颅减小。身高与TSH负相关(r=-0.421,P<0.01),而与TT4正相关(r=0.463,P<0.01)。简要讨论了两者的关系。

【Abstract】 A research of the relationship between pituitary-thyroid axis and physical development in 42 cases of Qinghai endemic disease was reported,The pituitary enlargement in cretins was revealed by CT scan.The positive correlation between pituitary height and serum TSH was found(r=0.511, P<0.001),but the negative correlation with TT4(r=0.377, P< 0.05).The serum TSH in cretins was increased, particularly in the myxedematous.The physical development in cretins delayed.The cranium of cretins showed by CT scan was smaller than that of the normal. The negative correlation between height and Serum TSH was discoveted(r=0.421, P<0.01), but positive correlation with TT4(r=0.463, P< 0.01).The author discussed the both relaions.

  • 【文献出处】 青海医药杂志 ,Qinghai Medical Journal , 编辑部邮箱 ,1987年03期
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