【摘要】 对88例糖尿病人和对照组30名血栓素B₂（TXB₂）和6-酮-前列腺素F_1α(6-酮-PGF_1α)测定,发现糖尿病伴血管病变和对照组比较（P<0.05）有显著差异。两者的变化与血管病变,降糖药物应用后血管病变趋向稳定有一定关系,与血糖、胆固醇和三酸甘油的变化无相关性,TXB₂和6-酮-PGF_1α测定可作为糖尿病人高凝状态或有无血管病变的检测指标之一。更多还原

【Abstract】 The plasma concentration of thromboxane B₂ and 6-Keto-PGF_1α were determined in 88 patients of diabetes mellitus and 30 normal controls. This change in concentration occurred with higher significance in diabetes mellitus with angiopathy （P<0.05） as compared with the control group. The observed changes showed correlation between the angiopathy and its stability after using hypoglycemic drugs, and no correlation with the changes of blood sugar, cholesterol, and triglyceride. Hence, the plasma levels of thromboxane B₂ and 6-Keto-PGF_1α is useful as an index in determining the diabetes in hypercoagulation state with or without angiopathy.更多还原