【摘要】 本文报告一次大鼠的自发性痘病,其症状与小鼠传染性脱脚病相似,但致死率较低。以病鼠肝、脾为接种材料,人工感染小鼠能引起发病,并对IBRS₂传代细胞有致病变作用。取含毒细胞培养液经磷钨酸负染后电镜观察,发现有在形态上与痘病毒相似的病毒粒子,大小为250—350nm。更多还原

【Abstract】 This article reported a spontaneous pox infection in rats. Its clinic signs were similar to infectious ectromelia of mice, but mortality rate was lower. The disease was reproduced artificially in mice following inoculation with liver and spleen suspension of the sick rat. And the virus was isolated and a cytopathogenic effect was observed in IBRS, cell line.By phosphotungstic acid negative staining, under the electron microscope viral particles which were morphologically to be similar to poxvirus, 250-350 nm in diameter in the infected IBRS2 cell were photographed.更多还原