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淋巴瘤间质反应性组织细胞和网状细胞增生的特点

GROWTH PATTERNS OF DIFFERENT INTERSTITIAL HISTIOCYTES AND RETICULUM CELLS IN LYMPHOCYTIC LYMPHOMA

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【作者】 曹鸣陈钦材刘开凤周幼斌

【Author】 Cao Ming;Chen Qincai(Chen Chin-Tsai);Liu Kaifeng;Zhou Youbin Department of Pathology

【机构】 华西医科大学病理学教研室华西医科大学病理学教研室

【摘要】 作者取76例不同类型淋巴细胞性淋巴瘤患者的淋巴结,分别作5种酶组化染色和3种抗体的免疫组化染色,探讨其间质反应性组织细胞和网状细胞增生的特点。结果发现;病变内各种组织细胞和网状细胞的增生程度有很大的差异,且具有不同的分布规律。

【Abstract】 Frozen and paraffin sections of lymphnodes from 76 cases with different morpho-logic and immunologic types of Iymphocyticlymphoma were stained for acid α-naph-thyl acetate esterase, acid phosphatase, a-denosine triphosphatase, 5’-nucleotidase andalkaline phosphatase enzymehistochemically,α1-antitrypsin, α1-antichymotrypsin andS-100 protein immunohistochemically toinvestigate the growth pattern of differenthistiocytes (HC) and reticulum cells (RC).The results showed that the types of HCand RC proliferated in different degrees.While HC and dendritic/interdigitating RCwere distributed irregularly, RC and fibro-blastic RC proliferated correlating with thehistologic/immunologic type and malignantgrade of tumors. This showed that eachtype of HC/RC had its own characteristicsof proliferation and distribution. The pa-thological significance of different HC andRC present in tumors were also discussed.

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