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某生活区大气污染对儿童淋巴细胞转化率的影响

THE EFFECT OF AIR POLLUTION ON LYMPHOCYTE TRANSFORMATION RATE IN CHILDREN

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【作者】 朱振华谭宗庆易振凯邓永坤

【Author】 Zhu Zhenhua;Tan Zongqing Department of Environmental Hygiene Yi Zhenkai;Deng Yongkun Institute of Labour Health Protection

【机构】 华西医大环境卫生学教研室华西医大劳动卫生防护研究所华西医大劳动卫生防护研究所

【摘要】 本文报道某公司大气污染区134例8~13岁儿童外周血淋巴细胞转化率(淋转率)与对照区155例儿童淋转率比较,有高度显著性差异(P<0.001),表明大气污染区儿童的细胞免疫功能有所下降。并介绍一种测定淋转率的方法,用血量少(0.2ml)、操作简便、不需特殊设备,适于基层人群调查检测之用。

【Abstract】 This paper reports the in vitro lympho-cyte transformation rate (LTR) of the peri-pheral blood of children in different airpollution areas of a steel complex.The annualair monitoring showed that the concentrationsof suspended particulates and SO2 in thepolluted area were significantly higher thanthat in the control area.The average LTR of134 children, 8 to 13 yr of age in the pollutedarea was 62.38% and that of 155 children, 8to 13 yr of age in the control area was 68. 59%.There was a great significant difference ofLTR between the two groups of children (P<0. 001).The results showed that the cellularimmune function of the children in the pol-luted area was lower than that in the controlarea. But there was no sex difference betweenthe LTR of male and female children in thesame area. In this paper a simple, reliable and eco-nomic method for detecting LTR is introduced.It can be applied to mass survey at the basichealth units.

【关键词】 大气污染淋巴细胞转化率
【Key words】 Air pollutionLymphocyteTransformation rate
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