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硝苯吡啶治疗高血压病疗效分析

ANALYSIS OF ANTI-HYPERTENSIVE EFFECT OF NIFEDIPINE

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【作者】 周宏研; 胡凯; 孙明; 王智纯; 郭远能; 王振华;

【Author】 Zhou Hongyan;Hu Kai;Sun Ming;Wang Zhichun;Guo Yuanneng;Wang Zhenhua Department of Internal Medicine,The First Affiliated Hospital,Hunan Medical College

【机构】 湖南医学院第一附属医院内科; 湖南省商业厅职工医院; 湖南医学院第一附属医院内科;

【摘要】 用国产硝苯吡啶(心痛定)口服治疗高血压病患者36例,症状及降压疗效分别达94.4%及83.3%,效果满意,心功能有明显改善,在降低血压的同时,有改善心脏功能作用,因而可做为一种有前途的降血压药物。

【Abstract】 Thirty-six patients with mild or moderate hypertension were treated withnifcdipine for two to three months.The drug relieved symptoms,especiallyhee.daches,in 94.4% of the patients.Nifedipine lowered blood pressure in 83.3%of the patients with 70% reaching normaldiastolic levels.These levels were achieved within a week and remained steady throughout the observation period.When diastolic heart function was checked at the end of the study period,theA/H and A/D ratios were shown to be decreased as compared to levels beforetreatment,the A2OI and DATI were prolonged all to a statistically significantdegree.Above changes reflect the improvement of diastolic heart function.It isconsidered that nifedipine could be a valuable anti-hypertensive agent.

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