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广州地区“秋季腹泻”前后期人群中轮状病毒感染的血清学调查

Serologic Research of Human Rotavirus Infection Before and After the Epidemiology of"Autumn Diarrhea"in Guangzhou

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【作者】 杨英马桂璋梁希若郑伯建韩守信严泳楷谢建屏常汝虚

【Author】 Yang Ying Department of Microbiology

【机构】 广州医学院广州医学院中山医科大学广州市儿童医院

【摘要】 本研究用酶联免疫吸附试验(ELISA),对"秋季腹泻"流行前后,从出生到50岁的543份正常人血清,进行了轮状病毒抗体 IgM、IgA、和 IgG 水平的调查,并随机抽样10份阳性血清,用 ELISA 阻断试验证明确为 HRV 的特异性抗体。结果表明,三种抗体阳性率均为流行期后高于流行期前,尤以 IgM 为明显,从年龄组来看,1岁以下组最低,但亦已达90.9%,以后随年龄加大而增高,而2岁以上各组均已达100%。另外,还发现≤6月组的 IgA 水平较高。

【Abstract】 The levels of HRV specific antibodies IgM,IgA and IgG have been measured by enzyme-linked immunospecific assay(ELISA)in 543 cases occuring before and after the epidemic of "Autumn diarrhea" in Guangzhou. The results demonstrated that the positivity rates of these 3 classes of antirotavirus immunoglobulin were higher after the epidemic than before the epidemic,espcially serum IgM.The possitivity rate in the six-month group is the lowest(91%),it increased with age,and reached 100% in the two- year group. In addition,the possitivity rate of IgA was the highest in the group under 6 months.

  • 【文献出处】 广州医学院学报 ,Academic Journal of Guangzhou Medical College , 编辑部邮箱 ,1987年02期
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