【摘要】 本文报告一家族六代90人中患Marie共济失调者12人(13.3％),系谱完整可靠。临床特点表明:本病属常染色体显性遗传并具明显的“早发”现象。连续四代调查可见子代比亲代发病年龄提早10年左右,临床症状亦逐代加重。更多还原

【Abstract】 There were 12 cases of Marie’s Ataxia among 90 individuals of 6 generations in one family. The Dedigree was complete and reliable. The conclusion is that the disease is somatic chromosome dominant inheritance. It has a tendency of "earlier episode". The investigation at continuous 4 generations showed that the age of episode in the next generation was younger than the previous about 10 years, and the later the generation get. the more severe the clinical symptoms were.更多还原