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中国人(辽宁地区)PGM1亚型的分布及一例PGM1china罕见型的报导
Distribution of Phosphoglucomutase-1(PGM1) subtype in Chinese with a Special Reference to the PGM1 China Variant
【摘要】 <正> 1964年Spencer, Hopkinson及Harris在用淀粉凝胶电泳对人类红细胞内酶类的研究中首次检测出由PGM11位点上的两个常见等位基因(PGM11和PGM12)所决定的3个常见表现型:PGM11、PGM12及PGM12—1。后来,不少学者对PGM1进,行了进一步的研究,相继发现了一些罕见等位
【Abstract】 A total of 320 unrelated individuals from the Liaoning area, China, have been t ped for red cell PGM1 using isoelectric focusing(PH5—7) in thin—layer polyacry lamide gels. 10 subtypes are considered as gene products of 4 alleles at PGM1 locus with the following frequencies. PGM11+=0.6240, PGM11-=0.1240,PGM12+=0.1755, PGM12-=0.0765. A rare variant PGM18 as well as a new rare variant PGM1 China is reported and the pedigree study about this new variant has been carried out. T hePI of this new variant is also determined. The discriminatingpowe(DP) of the PGM1 is 0.76. A example of the application PGM1 in individual identification case is attached to this paper.
- 【文献出处】 法医学杂志 ,Journal of Forensic Medicine , 编辑部邮箱 ,1987年02期
- 【被引频次】1
- 【下载频次】10