【摘要】 <正> 七十年代对於甾族化合物的CNMR谱研究主要采用质子噪音去偶、偏共振去偶、相关化合物比较,辅以同位素标记、镧系化学位移试剂和弛豫时间等技术。质子噪音去偶¹³C谱具有谱线简单和灵敏度高等特点,但失去了偶合信息。偏共振去偶谱保留了偶合信息,得到的J^r值虽较真正的¹J_CH值要小,一般说来能较有效地区分碳原子类型,但对甾族化合物因偶合的多重谱线彼此重叠,降低了用偏共振谱指配的有效性。目前,对於复杂化合物的¹³C谱更多还原

【Abstract】 By using the technique of distortionless enhancement by polarization transfer（DEPT） and quaternary carbon pulse sequence, C-13 NMR spectra of two epimeric 50-steroids urso deoxycholic acid（UDCA） and chenodeoxycholic acid （CDCA） were measured and their subspectra of CH₃, CH₂, CH, quaternary Cw were obtained by editing these results. The spectral lines of UDCA and CDCA were assigned by comparing with those of related compounds and consi dering the effect of the configuration of C-7 OH group on the chemical shifts ofα-,β-,and γ-C atomc.更多还原