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甲状腺机能亢进症并发二尖瓣脱垂(九例临床分析)

Hyperthyroidism Associated with Mitral Valve Prolapse (Clinicl Analysis of 9 Cases)

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【作者】 倪达人陈焕章王中心陈济添

【Author】 Yi Daren 1st Affiliated hospital

【机构】 福建省医学院附属第一医院内科福建省医学院附属第一医院内科

【摘要】 <正> 甲状腺机能亢进症(下称甲亢)并发二尖瓣脱垂(MVP)国内报道不多。几年来我们在住院及门诊的甲亢患者中经听诊和超声心动图检查发现9例,现报告如下。临床资料性别:女性6例,男性3例。年龄:22~64岁,平均年龄39.4岁,<45岁者7例。甲亢表现:8例有较典型的病史,病程自2个月至8年,平均3.1年。6例有轻至中度突眼,全部病例均有弥漫性甲状腺肿大,一般为2至3度。胸痛特点:8例有不同程度的心前区或左胸疼痛。轻者偶感短暂闷痛,重者呈针刺

【Abstract】 9 cases of hyperthyroidism with mitral valve prolapse(MVP)were reported, Most cases had typical history of hyperthyrodism and chest pain except case 6.Th- yroid funtion tests suggested characteristics of hyperthyroidism.Heart examinations showed mid-late or late systolic click in 7 cases and 9 cases presented signs of typ- ical MVP by M-mendel and two dimension echocardiography.Symptoms of hyperthyr- oidism and chest pain in 9 cases were relieved by administration of anti-thyroid drug and inderal.The follow-up of five cases the original pictures of MVP dissappeared in 3 cases and became indistinctive in 2 cases. This paper expressed certain relationship between hyperthyroidism and MVP. In addition to hereditary factor,auto-immunlogical mechanism inasmush as a comm- on basis for two diseases,there area close causality between them.This article discu- ssed the mechanism according relevent literature and also convinced that MVP is one of the diagnostic criterion for hyperthyroid heart disease and exhibits a newclin- ical manifestation of cardiovascular disease.

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