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山麦冬水溶性提取物亚急性毒性的实验观察
THE SUBACUTE TOXICTY STUDIES OF WATER-SOLUBLE EXTRACT OF LIRIOPE SPICATA LOUR(WSEL)
【摘要】 山麦冬水溶性提取物3g/kg、6g/kg、9g/kg给大鼠腹腔注射每天1次共2周,血尿素氮、GPT、Hb、Rbc、Wbc+Dc等指标均无明显改变。组织学检查表明,对其心、肝、脾、肺、肾未见明显毒性。
【Abstract】 In this paper,the subacute toxicity of WSEL on rats is reported. The results showed that through intraperitoneal injection of WSEL,in dosages of 3 g/kg, 6 g/kg and 9 g/kg respectively once daily to atotal time of two weeks, the values of blood urea nitrogen, GPT, Hb, Rbc and Wbc + DC did not show any significant change, and also, no significant toxic effects were found in the histological examination ofthe heart, the liver, the lung, the spleen and the kidney when compared with the control group. It is suggested that WSEL is a safe drug for clinical therapeutics.
【关键词】 山麦冬;
亚急性毒性;
组织学观察;
【Key words】 Liriope spicata lour; Subacute toxicity; Histologic examination;
【Key words】 Liriope spicata lour; Subacute toxicity; Histologic examination;
- 【文献出处】 大连医学院学报 , 编辑部邮箱 ,1987年04期
- 【被引频次】4
- 【下载频次】111