【摘要】 本文报告应用ELISA法测定包虫病人的血清总IgE水平和特异性抗包虫IgE的初步研究结果。118名正常人血清IgE水平的几何均值为639.41±1.81iu/ml;48例包虫病人为836.52±2.68iu/ml,二者有显著差异(p<0.05)。48例包虫病人特异性IgE抗体阳性率为83.33％。在9例IgG-ELISA阴性病人中,有6例IgE-ELISA阳性。病人血清IgE水平的上升与特异性IgE抗体检测强度之间呈正相关。提示包虫病人IgE水平的升高主要是由于特异性IgE抗体的增加。建议将特异性IgE的检测作为包虫病常规血清学检查内容之一,以提高检出率。更多还原

【Abstract】 The paper represents the results of determinations of IgE levels and specific IgE antibodies in sera of patients with hydatid disease. The geometric mean values of serum IgE from 118 normal persons and 48 cases with hydatidosis were 639.41±1.81iu/ml and 836.52±2.91iu/ml respectively. The specific IgE antibodies were detected in 40 out of 48 patients (83.33%) by indirect ELISA. In nine cases who were negative in IgG-ELISA, six were positive in specific IgE-ELISA. The elevation of IgE levels in sera of patients with hydatidosis correlated with the increase of specific IgE antibodies to E. granulosus. It is suggested that the elevation of IgE levels was mainly due to the production of specific IgE antibodies. It was recommended that the specific IgE antibody detection be included in routine serological examination of diagnosis in hydatid disease.更多还原